Template Wizard link | Template | Project/Provider | | Type | Category | Status |
DEFAULT
|
In-vitro assay
A generic dose response template.
|
/IOM |
|
doseresponse |
Cell Viability |
published |
COMET
|
COMET
The comet assay, also called SCGE (Single Cell Gel Electrophoresis), is a rapid and informative method to detect DNA damage at single cell level used on many different cell types. The assay detects single and double strand DNA breaks as a consequence of a direct damage or as intermediate of DNA repair processes and it is successfully applied both in in vivo and in vitro genotoxicity testing.
|
RISKGONE/NILU |
|
doseresponse |
Genetic toxicity in vitro |
published |
CFE
|
Colony Forming Efficiency
The colony forming efficiency assay (CFE) (also called clonogenic or plating efficiency assay) measures the ability of cells to survive and form colonies, which is an ultimate index of cytotoxicity.
|
RISKGONE/NILU |
|
doseresponse |
Cell Viability |
published |
ALAMARBLUE
|
Alamar Blue
The Alamar Blue (AB) assay is a high throughput, cell metabolism-based method largely applied in toxicology and nanotoxicology to investigate cell viability (cytotoxicity), cell proliferation and cellular metabolic activity in response to chemicals and nanomaterials.
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RISKGONE/NILU |
|
doseresponse |
Cell Viability |
published |
WST1
|
WST-1 Assay for Cell Proliferation and Viability
|
GRACIOUS/BfR |
|
doseresponse |
Cell Viability |
published |
NRU
|
Neutral Red Uptake Assay
|
GRACIOUS/BfR |
|
doseresponse |
Cell Viability |
published |
HPRT
|
HPRT gene mutation assay - SWANSEA layout
The hypoxanthine-guanine phosphoribosyl transferase (HPRT) gene is located on the X chromosome of mammalian cells and is used as a model gene to investigate gene mutation. The in vitro mammalian cell gene mutation assay is significantly important for detecting point mutations induced by engineered nanomaterials (ENMs) as the bacterial reverse gene mutation assay (Ames test) is not appropriate for use with these materials.
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RISKGONE/SWANSEA |
|
doseresponse |
Genetic toxicity in vitro |
published |
BARRIERCROSSING
|
Barrier crossing
|
NANOINFORMATIX/ |
|
doseresponse |
Barrier integrity |
published |
DEFAULT
|
In-vitro assay
A generic dose response template.
|
/IOM |
|
doseresponse |
Cell Viability |
published |
MICRONUCLEUS
|
Long-Term 3D cytokinesis-blocked micronucleus (CBMN) assay
The template for 3D cell models follows the structure of a 2D template. Still, it differs in the “Raw data” spreadsheet, where the metadata expected to be filled up follows the specificity of experiments to detect micronucleus in 3D spheroids (PATROLS, D4.1 SOPs for GIT and liver 3D advanced models optimised for long-term exposures.
|
PATROLS/SWANSEA |
|
doseresponse |
Genetic toxicity in vitro |
published |
CBMN
|
Acute 2D/3D cytokinesis-blocked micronucleus (CBMN) assay
The micronucleus assay is considered the gold standard for detecting chromosomal damage in vitro. The assay is designed so that cells exposed to a genotoxic test agent result in chromosomal breakage forming small spherical nuclei (micronuclei) being detected as fixed DNA damage.
|
NANOINFORMATIX/FIOH |
|
doseresponse |
Genetic toxicity in vitro |
published |
PC_GRANULOMETRY_GRACIOUS
|
Particle size distribution by ES-DMA, CLS (AUC)
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Particle size distribution (Granulometry) |
published |
PC_GRANULOMETRY_DLS
|
Hydrodynamic particle size by DLS
(CC BY-SA 4.0)
http://dx.doi.org/10.2787/505397
|
NANOREG/JRC |
|
pchem |
Particle size distribution (Granulometry) |
published |
PC_GRANULOMETRY_TEM
|
Particle size distribution by TEM
(CC BY-SA 4.0)
http://dx.doi.org/10.2787/505397
|
NANOREG/JRC |
|
pchem |
Particle size distribution (Granulometry) |
published |
PC_GRANULOMETRY_NTA
|
Particle size and particle counting by Nanoparticle Tracking Analysis
(CC BY-SA 4.0)
NTA technique provides size characterization based on the free diffusion behavior of particles in solution. NTA measures particle diffusion by tracking the random motion of single particles in solution via high temporal-resolution video acquisition and enhanced contrast microscopy. The diffusion of the objects in suspension is measured with single-particle resolution, and hence it is particularly suitable for the characterization of size distribution for highly polydisperse nanoparticle populations.
http://dx.doi.org/10.2787/505397
|
NANOREG/JRC |
|
pchem |
Particle size distribution (Granulometry) |
published |
PC_DUSTINESS
|
Dustiness with small drum
(CC BY-SA 4.0)
http://dx.doi.org/10.2787/505397
|
NANOREG/JRC |
|
pchem |
Dustiness |
published |
DENSITY_HEPYCNOMETER
|
Density - He Pycnometer
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Density |
published |
DENSITY_EFFECTIVE
|
Effective density
(CC BY-SA 4.0)
Multiple materials and results in JRC/NANoREG template style
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Density |
published |
ZETAPOTENTIAL
|
Zeta Potential
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Zeta potential |
published |
REDOXPOTENTIAL
|
Redox Potential
|
NANOINFORMATIX/ |
|
pchem |
Oxidative Stress |
published |
PC_SURFACECHEMISTRY_TGA
|
Surface Chemistry (TGA)
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Analytical Methods |
published |
PC_SURFACECHEMISTRY_FTIR
|
Surface Chemistry (FTIR)
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Analytical Methods |
published |
PC_SPECTRA_RAMAN
|
NANOREG Raman data template (updated by PLASTICFATE)
(CC BY-SA 4.0)
|
PLASTICFATE/CSIC |
|
pchem |
Analytical Methods |
published |
SSA_SEARSTITRATION
|
Specific Surface Area by Sears Titration (for colloidal silica)
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Specific surface area |
published |
SSA_BET
|
Specific Surface Area by BET (Brunauer, Emmett and Teller) method
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Specific surface area |
published |
HYDROPHOBICITY_CONTACTANGLE
|
Hydrophobicity by Contact Angle
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Water solubility |
published |
SURFACECHEMISTRY_XPS
|
Surface Chemistry by X-ray Photoelectron Spectroscopy (XPS)
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Surface chemistry |
published |
COMPOSITION_XRF
|
Elemental composition and chemical purity by X-ray Fluorescence (XRF)
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Analytical Methods |
published |
CRYSTALLINITY_XRD
|
Crystallinity by X-Ray diffraction (XRD)
(CC BY-SA 4.0)
http://dx.doi.org/10.2760/142959
|
GRACIOUS/JRC |
|
pchem |
Crystalline phase |
published |
ECOTOX
|
Ecotoxicity - fish, daphnia, algae, soil
(CC BY-SA 4.0)
http://dx.doi.org/10.2787/505397
|
NANOREG/JRC |
|
ecotox |
Short-term toxicity to aquatic inverterbrates |
published |
OMICS
|
Omics metadata
(CC BY-NC-SA 4.0)
А metadata map for omics data with columns relevant for nanosafety. Omics data stored in e.g. Gene Expression Omnibus (GEO), ArrayExpress, or PRIDE implement omics community standards, including minimum information requirements for omics experiments. However, the databases lack field-specific metadata, such as that defined within the nanosafety community, which leads to poor interoperability with other types of data and databases.
|
NANOREG2/KI |
|
metadata |
Omics metadata |
published |
OMICSINVIVO
|
Omics in-vivo metadata
(CC BY-NC-SA 4.0)
OMICS template extended with fields for in-vivo studies
|
HARMLESS/KI,NRCWE |
|
metadata |
Omics metadata |
published |